Grants for Science & Engineering R&D, Innovation Programs, STEM Education, & Workforce Development

Federal Grant Opportunities:  1,561 Topics With Cash Award Values Exceeding $17B!

New Search Option:  Interested in New Grant Opportunities:  Search for 161 New Opportunities>>>

Search Federal R&D Grant Opportunities by Topic


New Topics

Total Topics


161 1,561

Big Data & Data Analytics>>>


Centers of Excellence>>>

4 44

Conference & Workshop Support>>>

2 11

Health Software, Devices, Equipment, & Instrumentation>>>

9 88

Life Sciences>>>

64 941

Science, Engineering & Technology>>>

61 248

STEM Education & Faculty/Instructor Career Development>

16 200

Workforce Training & Development>>>

5 20


Search For Federal R&D Grant Opportunities By Agency 


New Topics

Total Topics

Department of Defense>>>

14 96

Department of Energy>>>

8 11


1 20

National Institute of Health>>> (NIH, HHS, CDC & FDA)

80 1,199

National Science Foundation>>>

43 190

All Other Agencies>>>

15 45

State of Florida Grant Opportunities  

Trade Grants

Target Sector Trade Show Grants

Enterprise Florida offers grants to help Florida companies grow their export sales through overseas international trade shows. Eligible small and medium-sized manufacturers and professional services providers can apply for a Target Sector Trade Show Grant to help offset trade show booth costs and enable them to exhibit in trade shows that Enterprise Florida participates in, as well as other approved trade shows and exhibitions in target sectors.

  • Target Sector Trade Show Grants provide reimbursable grants for eligible companies in one of Enterprise Florida’s target sectors to participate in a qualified trade show or exhibition anywhere in the world. Two reimbursement options are available for eligible companies.

Option A: Companies with 500 employees or less may qualify for reimbursement of 75% of trade show booth costs up to $7,500.

Option B: Companies with fewer than 100 employees AND participating in events within select target markets (Africa; Asia; Australia / New Zealand; Mexico, or Middle East) may qualify for reimbursement of 100% of trade show booth costs up to $10,000.

Gold Key/Matchmaker Grants

Eligible small and medium-sized manufacturers and professional services providers can apply for a Gold Key/Matchmaker Grant to help them generate or increase export sales overseas. The grant serves as a market development tool for companies that are new-or-infrequent exporters by subsidizing the cost of meeting with pre-screened and pre-qualified buyers, agents, importers, and representatives with an interest in their products or services.  Gold Key Services can be provided by the U.S. Commercial Service, while similar one-on-one business matchmakers can be conducted through select Enterprise Florida international offices or a pre-approved third-party such as an AmCham.

Gold Key/Matchmaker Grants reimburse qualified companies 100% of the Participation Fee for Enterprise Florida trade missions, or the full cost of a stand-alone Gold Key/Matchmaker service.  Other options are available. Click here for complete grant terms and conditions.

Export Marketing Plans

Enterprise Florida, in partnership with the Florida SBDC Network and the U.S. Commercial Service, offers qualified Florida manufacturers and services providers the development of a customized Export Marketing Plan to identify overseas growth strategies for the company. Upon completion of the Export Marketing Plan, new-to-export or infrequent exporters can apply for a reimbursable Gold Key/Matchmaker Grant, a Target Sector Trade Show Grant, or participate in an Enterprise Florida overseas trade mission.  Click here to complete the online application.

The cost to prepare an Export Marketing Plan is $4,000. Qualifying companies are eligible for a $3,500 grant, making the cost to your company $500.

“Florida Online Global” — Website Localization Grants

Globalize your website by making it local – with fully customized websites in your target markets. Enterprise Florida has teamed up with IBT Online to bring you the “Florida Online Global” program to help Florida exporters expand their overseas presence quickly and dynamically. Two options give you the flexibility to choose either a Two-Market Expansion or Multi-Market Web Presence.  Enterprise Florida offers qualifying companies an $8,000 grant for either option to reduce the costs to your company. 

Learn more>>>

Targeted Industry Incentives

Qualified Target Industry Tax Refund (QTI) - This incentive includes refunds on corporate income, sales, ad valorem, intangible personal property, insurance premium, and certain other taxes. Pre-approved applicants who create jobs in Florida receive tax refunds of $3,000 per net new Florida full-time equivalent job created; $6,000 in an Enterprise Zone or Rural Community (county).

Qualified Defense and Space Contractor Tax Refund (QDSC) - Florida defense, homeland security, and space business contractors a competitive edge in consolidating contracts or subcontracts, acquiring new contracts, or converting contracts to commercial production

Capital Investment Tax Credit (CITC) - The Capital Investment Tax Credit is used to attract and grow capital-intensive industries in Florida. It is an annual credit, provided for up to twenty years, against the corporate income tax. Eligible projects are those in designated high-impact portions of the following sectors: clean energy, biomedical technology, financial services, information technology, silicon technology, transportation equipment manufacturing, or be a corporate headquarters facility.

High Impact Performance Incentive Grant (HIPI) - The High Impact Performance Incentive is a negotiated grant used to attract and grow major high impact facilities in Florida.   In order to participate in the program, the project must: operate within designated high-impact portions of the following sectors– clean energy, corporate headquarters, financial services, life sciences, semiconductors, and transportation equipment manufacturing; create at least 50 new full-time equivalent jobs (if a R&D facility, create at least 25 new full-time equivalent jobs) in Florida in a three-year period; and make a cumulative investment in the state of at least $50 million (if a R&D facility, make a cumulative investment of at least $25 million) in a three-year period.

Learn more>>>Back To Top>>

Workforce Training Incentives

Quick Response Training Program (QRT) - An employer-driven training program designed to assist new value-added businesses and provide existing Florida businesses the necessary training for expansion. A state educational facility – community college, area technical center, school district or university – is available to assist with application and program development or delivery.

Incumbent Worker Training Program (IWT) - a program that provides training to currently employed workers to keep Florida’s workforce competitive in a global economy and to retain existing businesses. The program is available to all Florida businesses that have been in operation for at least one year prior to application and require skills upgrade training for existing employees.

Learn more>>> 

Special Opportunity Incentives

Rural Incentives: Florida encourages growth throughout the state by offering increased incentive awards and lower wage qualification thresholds in its rural counties. Additionally, a Rural Community Development Revolving Loan Fund and Rural Infrastructure Fund exist to meet the special needs that businesses encounter in rural counties.

Urban Incentives: Florida offers increased incentive awards and lower wage qualification thresholds for businesses locating in many urban core/inner city areas that are experiencing conditions affecting the economic viability of the community and hampering the self-sufficiency of the residents.

Brownfield Incentives: Florida offers incentives to businesses that locate on a brownfield site with a Brownfield Site Rehabilitation Agreement (BSRA). The Brownfield Redevelopment Bonus Refund is available to encourage Brownfield redevelopment and job creation. Approved applicants receive tax refunds of up to $2,500 for each job created. 

Learn more>>>Back To Top>>

Florida Translational Research Program   

The purpose of the Florida Translational Research Program (FTRP) is to produce a pipeline of potential new medicines based upon laboratory research discoveries. The Program provides Florida-based scientists with access to experienced professionals and state-of-the-art technological resources for drug discovery to facilitate an interdisciplinary, collaborative approach to establish a pipeline of potential new treatments for today’s most challenging and unmet medical needs. The Program is funded by the state of Florida through the Florida Department of Health and is administered and performed by the Sanford Burnham Prebys Medical Discovery Institute at Lake Nona.The Program is funded by the state of Florida through the Florida Department of Health and is administered by Sanford-Burnham Medical Research Institute at Lake Nona.

The goals of the FTRP are to implement a variety of innovative biochemical and cell-based assays to interrogate biological targets or processes for which there are limited selective and potent small-molecule modulators available; to execute high-throughput screens; and to develop lead compounds suitable for use in vivo.

Eligibility:  Researchers from Florida public and private colleges and universities, and established research institutions operating within Florida

Learn more>>>

Back To Top>>